Drug intelligence / Profile preview

Abroma Augusta

Development stage
Unknown
Administration
Oral, Topical
01

Overview

Abroma Augusta is a medicinal plant native to India and parts of Southeast Asia, commonly known as Devil's Cotton. It has a long history of traditional use in Ayurvedic and homeopathic medicine for various conditions, particularly diabetes and gynecological disorders. ## Botanical Information Abroma Augusta belongs to the Malvaceae family (sometimes classified under Sterculiaceae). It's an evergreen shrub found throughout the hotter parts of India, including Sikkim, Khasia hills, and Assam. The plant is known by various vernacular names across different languages: - Hindi: Ulat Kambal - English: Devil's Cotton - Tamil: Sivappututti - Bengali: Olatkaombol - Sanskrit: Yoshini, Pivari ## Medicinal Properties and Uses The medicinal parts primarily used are the root, root bark, and leaves. The plant contains several active compounds including: - Abromine (alkaloid) - Friedelin - Abromasterol - Choline betaine In Ayurvedic medicine, Abroma Augusta is characterized by: - Taste (Rasa): Pungent (Katu), Bitter (Tikta) - Properties (Guna): Light (Laghu), Dry (Rooksha) - Post-digestive effect (Vipaka): Pungent (Katu) - Potency (Veerya): Hot (Ushna) - Effect on Doshas: Balances Kapha and Vata ## Therapeutic Applications ### Diabetes Management Abroma Augusta has shown significant antidiabetic properties. Research indicates that the leaf extract can reduce hyperglycemia, hyperlipidemia, membrane disintegration, and oxidative stress in type 2 diabetes. It helps protect against diabetes-associated nephropathy and cardiomyopathy. ### Gynecological Disorders The plant is traditionally used for: - Amenorrhea (absence of menstruation) - Dysmenorrhea (painful menstruation) - Uterine disorders - Female infertility ### Other Conditions Abroma Augusta is also used for: - Albuminuria - Insomnia and sleeplessness - Debility and general weakness - Vertigo - Arthritis and joint pain - Bronchitis - Headache - Skin conditions (boils, carbuncles) ## Homeopathic Applications In homeopathy, Abroma Augusta is prepared as a mother tincture from the leaves or roots. It's prescribed for: ### Urinary Symptoms - Increased and frequent urination (especially at night) - High specific gravity of urine - Excessive thirst with dry mouth - Tiredness after urination - Whitish, foam-like sediment in urine - Burning sensation in urethra ### Male Reproductive Issues - Weakness of sexual organs - Exhaustion after coition - Swelling of testes ### Female Reproductive Issues - Irregular menstruation - Colicky pain in lower abdomen before menstruation - Dark, clotted blood during menstruation - Dysmenorrhea and amenorrhea ### General Symptoms - Burning sensation throughout the body - Weakness with weight loss - Pain relieved by lying down - Sleeplessness - Vertigo with empty feeling in head ## Dosage and Administration - Powder: 1-3 g - Fresh juice: 5-10 ml - Mother tincture: 30-40 drops with half a cup of water three times a day before meals - Homeopathic potencies: Q, 6C, 30C, and 200C ## Scientific Evidence Research has demonstrated that Abroma Augusta has: - Hypoglycemic effects (both in vivo and in vitro) - Antioxidant properties - Anti-inflammatory effects - Potential anticancer activities A study published in 2015 showed that the defatted methanol extract of Abroma Augusta leaves could attenuate diabetes and its associated nephropathy and cardiomyopathy in experimental rats by reducing oxidative stress and preventing cell death pathways. Abroma Augusta represents a valuable medicinal plant with multiple therapeutic applications, particularly for diabetes management and gynecological disorders, supported by both traditional knowledge and emerging scientific evidence.

Other names
Devil's CottonUlat KambalSivappututtiOlatkaombolYoshiniPivari
02

Targets

NF-κBBCL-2 (BCL-2 family)

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