Drug intelligence / Profile preview

Abrysvo

Development stage
Approved
Lead developer
Pfizer
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**Abrysvo** is Pfizer's bivalent recombinant respiratory syncytial virus vaccine composed of equal amounts of stabilized prefusion fusion glycoprotein F antigens representing RSV subgroup A and RSV subgroup B. It induces neutralizing immune responses directed at prefusion RSV F, thereby preventing RSV-associated lower respiratory tract disease. In the United States, it is approved for adults aged 60 years and older, adults aged 18 through 59 years at increased risk of RSV lower respiratory tract disease, and maternal immunization at 32 through 36 weeks' gestation to protect infants from birth through 6 months of age. ([labeling.pfizer.com](https://labeling.pfizer.com/ShowLabeling.aspx?id=21109))

Brand names
Abrysvo
Other names
RSVpreFrespiratory syncytial virus vaccinerespiratory syncytial virus vaccine bivalent recombinantRSV stabilized prefusion F subunit vaccine
02

Targets

Major histocompatibility complex class II (MHC II) molecule presenting carrier-protein peptideCPS (Streptococcus pneumoniae capsular polysaccharide)BCR-SpCPS (B-cell receptor specific for Streptococcus pneumoniae capsular polysaccharide)

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