Drug intelligence / Profile preview

ABS-002

Development stage
Preclinical
Lead developer
Alpha Biomedical
Modality
Stem Cell Therapies → Cell Therapies
01

Overview

ABS-002 is a mesenchymal stem cell (MSC) therapy under development by Alpha Biomedical for the treatment of osteoarthritis. Currently in the preclinical stage, the therapy leverages the regenerative and immunomodulatory properties of MSCs to address joint degeneration. MSCs are hypothesized to promote cartilage repair and reduce synovial inflammation through the secretion of paracrine factors and direct cell-to-cell interactions, potentially offering a disease-modifying approach for patients with osteoarthritis.

02

Targets

IL-15R (Interleukin 15 receptor alpha/interleukin 15 complex)CD274 (Programmed cell death protein 1 ligand 1)PDCD1LG2 (Programmed cell death 1 ligand 2)

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