Drug intelligence / Profile preview

ABS-003

Development stage
Preclinical
Lead developer
Alpha Biomedical
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

ABS-003 is an investigational natural killer (NK) cell therapy currently in preclinical development by Alpha Biomedical. Designed for the treatment of breast cancer, the therapy leverages the innate immune system's ability to identify and destroy malignant cells. NK cells are cytotoxic lymphocytes that can induce apoptosis in tumor cells through the release of perforin and granzymes or via death receptor-mediated pathways. As an adoptive cell therapy, ABS-003 aims to provide a potent immune response against solid tumors in the breast.

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