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ABV-1505
- Development stage
- Unknown
- Lead developer
- ABVC BioPharma
- Modality
- Small Molecules
01
Overview
ABV-1505 is a botanical drug candidate developed for the treatment of adult Attention Deficit Hyperactivity Disorder (ADHD). It is based on traditional Chinese medicine and utilizes the active pharmaceutical ingredient PDC-1421, which is derived from the plant Polygala tenuifolia (Radix Polygala). Clinical studies have shown that ABV-1505 demonstrates efficacy in improving ADHD symptoms with a favorable safety profile and minimal side effects. The drug has undergone Phase I and Phase II clinical trials, including randomized, double-blind, placebo-controlled studies at major research centers such as UCSF Medical Center and several hospitals in Taiwan. The mechanism of action involves modulation of brain pathways associated with mood regulation and cognitive function; however, the precise molecular targets remain undisclosed[1][2][6][7].
- Brand names
- ABV-1505ABV1505ABV 1505
- Other names
- PDC-1421PDC1421PDC 1421
02
Targets
NET (Norepinephrine Transporter)
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