Drug intelligence / Profile preview

acacia gum allergen extract + ctenocephalides canis allergen extract + ctenocephalides felis allergen extract + karaya gum allergen extract + tragacanth gum allergen extract

Development stage
Approved
Lead developer
Nelco Laboratories
Modality
Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intradermal, Percutaneous
01

Overview

This is an allergenic extract product manufactured by Nelco Laboratories, Inc. formulated as an injectable solution. [2, 5] The product is a combination of five components: allergens from Ctenocephalides canis (dog flea) and Ctenocephalides felis (cat flea) are the primary active ingredients, combined with tragacanth gum, karaya gum, and acacia gum. [10] While the gums can function as excipients, they are also recognized as potential allergens themselves. [4, 8, 17] The product is indicated for both diagnostic testing (e.g., skin tests) and for therapeutic use in allergen-specific immunotherapy (hyposensitization) for patients with allergic disease confirmed by history and skin test reactivity. [3, 11] The mechanism of action for immunotherapy involves the repeated administration of the allergens to desensitize the immune system, leading to an increase in blocking IgG antibodies and a reduction in the IgE-mediated response that causes allergic symptoms. [3]

Other names
tragacanth + karaya gum + acacia + ctenocephalides canis + ctenocephalides felis

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