Drug intelligence / Profile preview

acacia nilotica extract

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical, Vaginal
01

Overview

Acacia nilotica extract is a botanical extract derived from the *Acacia nilotica* tree (also known as *Vachellia nilotica*, babul, or kikar). It is rich in bioactive phytochemicals, including polyphenols, condensed tannins, phlobatannins, alkaloids, and flavonoids. The extract is traditionally used in ethnomedicine and is being pharmacologically evaluated for its anti-inflammatory, antioxidant, antimicrobial, and wound-healing properties. In preclinical models, it has demonstrated protective effects against ovalbumin-induced allergic asthma by reducing airway inflammation, mucus overproduction, and cytokine dysregulation (such as IL-4, IL-5, IL-10, IL-13, and IL-17A). Clinical trials have also investigated its efficacy as a mouthrinse to improve postoperative wound healing and reduce complications like alveolar osteitis following third molar surgery, as well as in the syndromic management of abnormal vaginal discharge.

Other names
Acacia nilotica extractAcacia nilotica flower extractAcacia nilotica gum extractAcacia nilotica leaf extractAcacia nilotica pod extractVachellia nilotica extractbabul extractkikar extract
02

Targets

CASP9 (Caspase-9)DNADHFR (Dihydrofolate reductase)ATP4A (Potassium–transporting ATPase alpha chain 1)LSS (Lanosterol synthase)CaV (Voltage-gated calcium channel protein complex)

Beyond the preview

Go deeper on acacia nilotica extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on acacia nilotica extract.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call