acanthopanax senticosus polysaccharide

Acanthopanax senticosus polysaccharide (ASPS) is a bioactive carbohydrate polymer extracted from the roots or rhizomes of *Acanthopanax senticosus*, commonly known as Siberian Ginseng or Ciwujia. It is widely recognized for its potent immunomodulatory, anti-tumor, and anti-inflammatory properties. Research indicates that ASPS exerts anti-colorectal cancer effects by modulating the gut microbiota-metabolism-immune axis, specifically by inhibiting the TLR4/MyD88/NF-κB signaling pathway. This inhibition leads to reduced inflammatory cytokine production and metabolic reprogramming of tumor cells. Additionally, ASPS is utilized as an adaptogen to enhance immune function and alleviate fatigue.

Other names

Eleutherococcus senticosus polysaccharideSiberian ginseng polysaccharideCiwujia polysaccharide