Drug intelligence / Profile preview

ACC006

Development stage
Unknown
Lead developer
AIDEA PHARMA
Modality
Small Molecules
Administration
Oral
01

Overview

ACC006 is an orally administered small molecule drug under development primarily for the treatment of squamous non-small cell lung cancer (NSCLC). It acts as an inhibitor of the mechanistic target of rapamycin (mTOR), a key regulator in cell growth and proliferation pathways. The drug has been studied both as monotherapy and in combination with other agents such as tislelizumab (a PD-1 inhibitor) and with albumin-bound paclitaxel plus carboplatin, targeting advanced or recurrent/metastatic NSCLC. Development is led by Jiangsu Aidea Pharmaceutical, with clinical trials conducted in China[1][2][3][5][9].

02

Targets

mTOR (Mammalian target of rapamycin kinase)SHH (Sonic hedgehog)

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