Drug intelligence / Profile preview

ACCS100

Development stage
Phase 2
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Small Molecules, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

ACCS100 is a naturally occurring clay-based compound investigated for its ability to reduce aflatoxin exposure and toxicity in humans. Its primary mechanism of action is believed to be the adsorption of aflatoxins in the gastrointestinal tract, thereby reducing their bioavailability and subsequent toxic effects. The drug has been evaluated in Phase 2 clinical trials for prevention of aflatoxicosis, particularly in regions with high dietary exposure to aflatoxins such as Kenya. It has also been studied for acute pain, liver failure (acute), abdominal pain, and carcinogenesis.

Brand names
Novasil
Other names
ACCS100ACCS-100ACCS 100

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