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**AccuVAC-D002** is an autologous dendritic cell based cancer vaccine being developed by Defence Therapeutics for melanoma. It uses the company's AccuTM intracellular delivery platform to enhance loading and cross-presentation of tumor antigens by dendritic cells, with the goal of improving activation of antigen-specific anti-tumor T-cell responses. Public descriptions indicate it was being advanced toward first-in-human clinical testing, with manufacturing activities underway and Phase I preparation for melanoma reported in the 2021 to 2022 period.
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