Drug intelligence / Profile preview

aceclofenac

Development stage
Phase 3
Lead developer
Almirall
Modality
Small Molecules
Administration
Oral, Topical, Intramuscular
01

Overview

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) and an analog of diclofenac. It is primarily used to relieve pain and inflammation associated with chronic musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Aceclofenac works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the synthesis of prostaglandins—mediators involved in pain, swelling, inflammation, and fever. Compared to other NSAIDs like naproxen or indomethacin, aceclofenac has a lower incidence of gastrointestinal side effects[1][3][5][7][10]. It is typically administered orally as film-coated tablets.

Brand names
PreservexAbateAbdalAcewalkAcicareAcicloflexAcidolAcifactAceron-SPAceroz-PAcer-P
Other names
2-[2-(2,6-dichloroanilino)phenyl]acetoxyacetic acid
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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