Drug intelligence / Profile preview

aceclofenac + paracetamol + serratiopeptidase (Zinnia Life Sciences)

Development stage
Unknown
Lead developer
Zinnia Life Sciences
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Zinidol-SP is a fixed-dose combination oral tablet containing the non-steroidal anti-inflammatory drug (NSAID) aceclofenac, the analgesic and antipyretic paracetamol, and the proteolytic enzyme serratiopeptidase. Developed by Zinnia Life Sciences, it is indicated for the relief of severe pain, swelling, and inflammation associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, as well as post-operative inflammation and dental pain. Aceclofenac and paracetamol work synergistically to inhibit prostaglandin synthesis via cyclooxygenase (COX) pathway blockade, while serratiopeptidase promotes the breakdown of fibrin and reduces fluid viscosity at inflammatory sites to facilitate drainage and alleviate edema.

Brand names
Zinidol-SP
Other names
Aceclofenac, Paracetamol & Serratiopeptidase TabletsZinidol SP
02

Targets

BK (Bradykinin)Fibrin (Factor Ia)PGHS-1 (Prostaglandin G/H Synthase 1)

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