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aceclofenac + paracetamol (Modi Lifecare Industries)
- Development stage
- Unknown
- Lead developer
- Modi Lifecare Industries
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Clofem Plus is a fixed-dose combination medication containing aceclofenac and paracetamol, manufactured by Modi Lifecare Industries. It is categorized as an analgesic, antipyretic, and non-steroidal anti-inflammatory drug (NSAID). Aceclofenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins that mediate pain and inflammation. Paracetamol provides additional analgesic and antipyretic effects, primarily through central nervous system mechanisms. The combination is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
- Brand names
- Clofem Plus
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)Prostaglandin-endoperoxide synthase (PGHS) peroxidase site
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