Drug intelligence / Profile preview

aceclofenac + paracetamol (Varmed Pharma)

Development stage
Unknown
Lead developer
Varmed Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Pureace is a marketed fixed-dose combination analgesic and anti-inflammatory medication containing aceclofenac and paracetamol. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the production of inflammatory prostaglandins. Paracetamol (acetaminophen) acts as an analgesic and antipyretic, primarily targeting the central nervous system to elevate the pain threshold and reduce fever. Together, these active ingredients provide synergistic relief from pain, swelling, and fever. It is commonly prescribed for the management of acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and post-surgical inflammation.

Brand names
PureacePureace-P
Other names
aceclofenac and paracetamolaceclofenac/paracetamol
02

Targets

GDF15 (Growth differentiation factor 15)PGHS-1 (Prostaglandin G/H Synthase 1)

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