acepifylline

Acefyl is a brand of bronchodilator medications developed and manufactured by Nabiqasim Industries, primarily containing **acepifylline** (acefylline piperazine). Acepifylline is a xanthine derivative related to theophylline that acts as a bronchodilator and respiratory stimulant. Its primary mechanism of action involves the non-selective inhibition of phosphodiesterase (PDE) enzymes, which leads to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels, resulting in the relaxation of bronchial smooth muscle. Additionally, it acts as an adenosine receptor antagonist. Acefyl is indicated for the symptomatic treatment of respiratory disorders associated with bronchospasm, such as bronchial asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). The product line includes a single-agent formulation (Acefyl 125) and a multi-ingredient expectorant variant (Acefyl Cough) which contains additional components like diphenhydramine and ammonium chloride.

Brand names

AcefylAcefyl 125Acefyl125Acefyl-125Acefyl Cough

Other names

acefylline piperazine7-theophyllineacetic acid piperazine saltacefylline