acetaminophen + dextromethorphan + guaifenesin + phenylephrine

Acetaminophen + dextromethorphan + guaifenesin + phenylephrine is an over-the-counter (OTC) fixed-dose combination medication widely used to relieve symptoms of the common cold, influenza, and upper respiratory allergies. The combination contains four active ingredients with distinct mechanisms of action: acetaminophen, a non-opioid analgesic and antipyretic; dextromethorphan, a centrally acting cough suppressant; guaifenesin, an expectorant that thins and loosens bronchial secretions; and phenylephrine, a sympathomimetic nasal decongestant. Together, these components temporarily relieve headache, fever, minor body aches, sore throat, cough, chest congestion, and nasal or sinus congestion. It is marketed under numerous well-known brand names, including DayQuil, Mucinex, Tylenol, and Theraflu, and is available in various oral dosage forms such as tablets, caplets, softgels, and liquid solutions.

Brand names

Alka-Seltzer Plus Day Severe Cold & FluAlka-Seltzer Plus Severe Sinus, Cold & CoughDayQuil Severe Cold & FluDelsym Cough + ColdDelsym Cough Plus Cold Day TimeMooreBrand Severe Cold ReliefMucinex Children's Cold & FluMucinex Children's Cold, Cough & Sore ThroatMucinex Children's FreeFrom Daytime Multi-SymptomMucinex Children's FreeFrom Daytime/NighttimeMucinex Children's Multi-Symptom Cold & Sore ThroatMucinex Cold, Flu & Sore ThroatMucinex Fast Max Kick StartMucinex Fast-MaxMucinex Fast-Max Cold & FluMucinex Fast-Max Cold, Flu & Sore ThroatMucinex Fast-Max Severe ColdMucinex Fast-Max Severe Congestion & ColdMucinex Freefrom Cold & Flu DaytimeMucinex Junior Cold & FluMucinex Multi-Symptom Cold and Fever Children'sMucinex Sinus-MaxPhenflu DMPhenflu GRobitussin CF MAX Severe Multi-Symptom Cough Cold + FluSine-Off Cold and CoughSudafed Cold and CoughSudafed PE Cold & CoughSudafed PE Cold and CoughSudafed PE Head Congestion + FluSudafed PE Pressure + Pain + ColdTheraflu ExpressMax Severe Cold & CoughTylenol ColdTylenol Cold & Flu SevereTylenol Cold Multi-Symptom SevereTylenol Cold Multi-Symptom Severe DaytimeTylenol Cold Severe Head CongestionTylenol Cold+MucusTylenol Warming Cough and Severe CongestionVicks DayQuil Cold & Flu

Other names

acetaminophen + dextromethorphan + guaifenesin + phenylephrineacetaminophen, dextromethorphan, guaifenesin, and phenylephrineacetaminophen/dextromethorphan/guaifenesin/phenylephrineacetaminophen/phenylephrine/dextromethorphan/guaifenesinguaifenesin + acetaminophen + dextromethorphan + phenylephrineguaifenesin, acetaminophen, dextromethorphan, and phenylephrineguaifenesin/acetaminophen/dextromethorphan/phenylephrine