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acetaminophen + gabapentin + scopolamine
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral, Transdermal, Intravenous, Rectal
01
Overview
A combination of three medications with different mechanisms of action. Acetaminophen is an analgesic and antipyretic used for mild to moderate pain relief. Gabapentin is an anticonvulsant used for seizures and nerve pain. Scopolamine is an antimuscarinic used for prevention of motion sickness and postoperative nausea and vomiting. This combination may be used for complex pain management and prevention of postoperative nausea, particularly when multiple mechanisms of pain and symptom control are needed.
02
Targets
TRPV1 (Transient receptor potential cation channel subfamily V member 1)CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)mAChR (Muscarinic acetylcholine receptors)CACNA2D2 (α2δ-2)CNR1 (Cannabinoid receptor 1)
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