Drug intelligence / Profile preview

acetaminophen + ibuprofen + caffeine (Fatak Chemie Pars)

Development stage
Unknown
Lead developer
Fatak Chemie Pars Pharmacy
Modality
Small Molecules
Administration
Oral
01

Overview

Panatec is a fixed-dose combination analgesic medication containing acetaminophen (paracetamol), ibuprofen, and caffeine, developed and manufactured by Fatak Chemie Pars Pharmaceuticals (FCP Pharma) in Iran. It is formulated as oral capsules containing 325 mg of acetaminophen, 200 mg of ibuprofen, and 40 mg of caffeine. Panatec is indicated for the temporary relief of mild to moderate pain, including headaches (such as tension headaches and migraines), toothaches, neuralgic-muscular pain, joint pain, and dysmenorrhea. Acetaminophen acts primarily in the central nervous system to inhibit prostaglandin synthesis, thereby reducing pain and fever. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that non-selectively inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, reducing peripheral prostaglandin synthesis and inflammation. Caffeine acts as a central nervous system stimulant and adenosine receptor antagonist, which enhances the analgesic efficacy of both acetaminophen and ibuprofen.

Brand names
AcifenFenbaseFenbase ExtraFenceta PlusIbex CapIbucapIbupar PlusIbuqueImol PlusIpeceePanatec
Other names
acetaminophen, ibuprofen, and caffeineparacetamol + ibuprofen + caffeineparacetamol, ibuprofen, and caffeine
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADORA2A (Adenosine A₂A Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)ADORA1 (Adenosine receptor A1 subtype)

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