Drug intelligence / Profile preview

acetylated sodium hyaluronate

Development stage
Unknown
Lead developer
Shandong Topscience Biotech
Modality
Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical, Subcutaneous, Ophthalmic
01

Overview

Acetylated sodium hyaluronate is a chemically modified derivative of hyaluronic acid developed by Shandong Topscience Biotech. By introducing acetyl groups onto the sodium hyaluronate backbone, the molecule gains amphiphilic properties, exhibiting both hydrophilic and lipophilic characteristics. This modification significantly enhances the ingredient's skin affinity and moisturizing capabilities compared to standard sodium hyaluronate. It is produced as a high-purity raw material in various quality grades, including medical device and pharmaceutical grades, for use in topical formulations, injectable medical devices, and ophthalmic products. The acetylation modification also provides improved stability and resistance to hyaluronidase degradation, making it a preferred ingredient for long-lasting hydration and barrier repair. In the cosmetic industry, it is marketed under the brand name ACEHYA.

Brand names
ACEHYA
Other names
Sodium acetylated hyaluronateMedical device grade acetylated sodium hyaluronateAcetylated hyaluronic acid sodium salt
02

Targets

CD44 (CD44 antigen)

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