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Acivia-RD
- Development stage
- Unknown
- Lead developer
- Arovia
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Acivia-RD** is an oral sustained-release capsule combination product marketed by **Arovia** for gastrointestinal disorders, particularly **gastroesophageal reflux disease** and **acid reflux**. It contains **domperidone + rabeprazole**, providing dual pharmacology: rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion via irreversible inhibition of the gastric **H+/K+-ATPase** in parietal cells, while domperidone is a peripheral **dopamine D2 receptor** antagonist with prokinetic and antiemetic activity that enhances gastric emptying and reduces reflux-promoting upper gastrointestinal stasis. The product appears to be a branded generic marketed formulation rather than a novel clinical-stage asset, with the sustained-release capsule presentation intended to provide prolonged symptom control.
- Brand names
- Acivia-RDAcivia-RD Capsule SR
02
Targets
DRD2 (Dopamine D2 Receptor)ATP4A (Potassium–transporting ATPase alpha chain 1)
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