Drug intelligence / Profile preview

AcneFree

Development stage
Unknown
Lead developer
AcneFree
Modality
Small Molecules
Administration
Topical
01

Overview

AcneFree is a brand of over-the-counter topical skincare formulations marketed for the treatment and prevention of acne. The products are generally sold as multi-step kits or individual treatments that target excess oil, clogged pores, and acne-causing bacteria. The core mechanism of action is the antimicrobial activity of benzoyl peroxide, which penetrates into pores to kill Cutibacterium acnes (the primary acne-causing bacterium) and reduce inflammation. Complementary ingredients include retinol (promoting exfoliation and skin cell turnover), witch hazel (astringent and mattifying effect), glycolic acid (alpha-hydroxy acid for exfoliation), niacinamide (anti-inflammatory and sebum-regulating), and others that support skin hydration and barrier function. AcneFree products are designed for daily topical application and are formulated to address mild to severe acne through a combination of active and supporting ingredients[1][2][5][10][13].

Brand names
AcneFree
02

Targets

Cutibacterium acnes cellular membranes and macromoleculesRARA (Retinoic acid receptor alpha)

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