Drug intelligence / Profile preview

aconiti lateralis radix praeparata

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

**Aconiti Lateralis Radix Praeparata** (熟附子, Fuzi) is the processed lateral root of *Aconitum carmichaelii* Debx., widely used in traditional Chinese medicine (TCM). It is known for its strong actions to restore yang from collapse, reinforce fire and strengthen yang, dispel cold to alleviate pain, and unblock meridians. The herb is indicated for conditions such as cold limbs, arthralgia (joint pain), impotence, edema, loose stool or constipation due to yang deficiency or cold accumulation. It must be carefully processed before use to reduce toxicity; improper processing or dosage can lead to severe adverse effects[1][2][3].\n\n**Mechanism of Action:** The main active compounds are diester-diterpenoid alkaloids such as aconitine, mesaconitine, and hypaconitine. These compounds have been shown in modern studies to possess anti-inflammatory and analgesic properties. Processing transforms highly toxic diester-diterpenoid alkaloids into less toxic monoester or non-esterified forms[2][4][9]. The herb acts by warming the body’s interior channels (meridians), invigorating heart and kidney yang energy, dispersing coldness from the body’s interior and channels.

Other names
熟附子FuziPrepared Aconite RootPrepared AconiteChinese WolfsbanePrepared Daughter Root of Common Monk's Hood
02

Targets

NaV (Voltage-gated sodium channels)

Beyond the preview

Go deeper on aconiti lateralis radix praeparata.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on aconiti lateralis radix praeparata.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call