Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Acorus calamus volatile oil is a complex essential oil extracted primarily from the rhizomes of the *Acorus calamus* plant, commonly known as sweet flag. It is characterized by its high concentration of phenylpropanoids, most notably **beta-asarone** and **alpha-asarone**, which are responsible for its broad pharmacological profile. The oil exhibits significant neuroprotective, sedative, and anticonvulsant properties, primarily through the modulation of the GABAergic system and the inhibition of acetylcholinesterase. Historically used in Ayurvedic and Traditional Chinese Medicine for cognitive enhancement and gastrointestinal disorders, modern research has focused on its potential in treating epilepsy and neurodegenerative diseases. However, its clinical development is strictly regulated in many regions, including the United States, due to the proven mutagenic and carcinogenic potential of the beta-asarone constituent, leading to the use of 'asarone-free' varieties for consumption.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on acorus calamus volatile oil.