Drug intelligence / Profile preview

Acoydase-Cold Tablets

Development stage
Unknown
Lead developer
Bernard Biotech
Modality
Small Molecules
Administration
Oral
01

Overview

Acoydase-Cold Tablets is an oral fixed-dose combination therapy developed by Bernard Biotech for the symptomatic relief of the common cold, nasal congestion, fever, and associated pain or body aches. The formulation contains five active ingredients: aceclofenac (a nonsteroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes to reduce pain and inflammation), paracetamol (an analgesic and antipyretic), cetirizine hydrochloride (a second-generation H1 antihistamine that alleviates allergic symptoms like runny nose and sneezing), phenylephrine hydrochloride (a selective alpha-1 adrenergic receptor agonist that acts as a nasal decongestant), and caffeine (a central nervous system stimulant that acts as an analgesic adjuvant and helps counteract drowsiness caused by antihistamines).

Brand names
Acoydase-ColdAcoydase-Cold Tablets
Other names
Aceclofenac, Paracetamol, Cetirizine Hydrochloride, Phenylephrine Hydrochloride, and Caffeineaceclofenac + caffeine + cetirizine + paracetamol + phenylephrineaceclofenac + caffeine + cetirizine hydrochloride + paracetamol + phenylephrine hydrochloride
02

Targets

ADORA2A (Adenosine A₂A Receptor)HRH1 (Histamine H1 Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)ADORA1 (Adenosine receptor A1 subtype)ADRA1A (α1A)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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