Drug intelligence / Profile preview

acp-105

Development stage
Unknown
Lead developer
Acadia Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

ACP-105 is a novel, nonsteroidal, orally bioavailable selective androgen receptor modulator (SARM) developed as a tissue-specific agonist of the androgen receptor[1][4][5]. It is designed to mimic the anabolic effects of androgens (such as increased muscle mass, bone density, and strength) while aiming to minimize the androgenic side effects commonly associated with traditional testosterone therapy, such as prostate enlargement, gynecomastia, and hair loss[1][3][5]. Preclinical studies have demonstrated potent anabolic effects on muscle and bone with minimal impact on the prostate, indicating tissue selectivity[3][4][5]. ACP-105 has also shown potential neuroprotective effects in animal models of ischemic stroke and has been investigated for effects on cognitive function, including protection against radiation-induced cognitive decline and enhancement of memory in certain contexts[1][6][11]. However, ACP-105 is not approved for medical use in humans and its safety profile remains insufficiently characterized[1][2]. It is classified as a performance-enhancing substance and is banned in sports[1][2].

Other names
2-Chloro-4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methyl benzonitrile
02

Targets

AR (Adrenergic receptors)

Beyond the preview

Go deeper on acp-105.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on acp-105.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call