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actarit
- Development stage
- Unknown
- Lead developer
- Nippon Shinyaku
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Actarit is a **disease-modifying antirheumatic drug (DMARD)** used primarily for the treatment of **rheumatoid arthritis**. Actarit is a small molecule, a phenylalkanoic acid derivative, developed in Japan. Its **mechanism of action** includes **modulation of interleukin-2 (IL-2) production**, leading to improved suppressor T cell activity, thereby **suppressing secondary inflammation** and reducing joint pain and swelling in autoimmune diseases. It also inhibits **carbonic anhydrase II (CAII)**. Actarit is not widely approved or marketed outside of certain Asian regions, particularly Japan. Side effects may include itching, rash, stomach pain, and hematuria.
- Brand names
- ActaritMobaMoverOrcl
- Other names
- 4-Acetylaminophenylacetic acid(p-Acetamidophenyl)acetic acidActaritumActrarit[4-(acetylamino)phenyl]acetic acidBenzeneacetic acid 4-(acetylamino)-
02
Targets
CA2 (Carbonic Anhydrase 2)IL-2 (Interleukin 2)RORC (Retinoic acid receptor-related orphan receptor gamma)
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