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Actifuse Flow is a synthetic bone graft substitute developed by Baxter International Inc. and cleared by the FDA in 2018 as a medical device. It is classified as a bone void filler for orthopedic applications, specifically designed for filling gaps in the skeletal system including the extremities, pelvis, and spine. The product utilizes a proprietary silicate-substituted technology that enhances silicon levels to accelerate bone formation. Delivered in a prepackaged, ready-to-use syringe, it maintains a flowable consistency during surgery and is eventually resorbed and replaced by the patient's natural bone during the healing process.
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