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activated autologous dendritic cells (LanZhou University)
- Development stage
- Unknown
- Lead developer
- Lanzhou University
- Modality
- Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
- Administration
- Intravenous
01
Overview
Activated autologous dendritic cells (LanZhou University) is an experimental personalized cancer vaccine and cell therapy being developed for the treatment of gastric cancer. The therapeutic process involves harvesting a patient's own dendritic cells (DCs) from peripheral blood and activating them in vitro using a cocktail of cytokines and proteins extracted from the patient's own tumor cell membranes. These activated DCs are then re-infused intravenously into the patient, typically as an adjuvant therapy following radical surgery. Once in the body, these professional antigen-presenting cells are intended to prime and activate the patient's T-cell population to recognize and eliminate residual tumor cells, thereby reducing the risk of recurrence and improving overall survival.
- Other names
- activated DCsautologous tumor cell membrane protein-activated dendritic cells
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