Drug intelligence / Profile preview

ActiveOxy

Development stage
Unknown
Lead developer
Aga Khan University
Modality
Small Molecules
Administration
Topical, Intranasal
01

Overview

ActiveOxy is a specific brand of 1% hydrogen peroxide solution that has been investigated as a topical antiseptic intervention for COVID-19. In a clinical trial led by Aga Khan University, the solution was utilized as both a gargling agent and a nasal lavage to reduce the intraoral and nasopharyngeal viral load in patients with mild to moderate disease. The mechanism of action involves the oxidative properties of hydrogen peroxide, which acts as a broad-spectrum antiseptic capable of debriding surfaces and potentially inactivating viral particles through the generation of free radicals that damage viral proteins and nucleic acids. This approach was studied as a cost-effective prophylactic and therapeutic adjunct to reduce viral shedding and protect healthcare workers in resource-limited settings.

Brand names
ActiveOxy
Other names
1% hydrogen peroxide solutionHydrogen peroxide 1%ActiveOxy-Aga Khan University-COVID-19
02

Targets

vRNA (Coronavirus viral RNA)

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