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**AcuPlus** is a marketed over-the-counter topical analgesic product from Innovations for Wellness. Its labeled active ingredient is menthol 3.5%, supplied as a cream for external topical use. Menthol produces a cooling counterirritant analgesic effect and is indicated for temporary relief of minor muscle and joint aches associated with arthritis, simple backache, strains, bruises, and sprains. The formula also includes supportive non-active ingredients such as aloe, arnica, MSM, glucosamine, magnesium sulfate, and vitamins. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=7f222a4f-85a8-4f3d-aa97-5c695d4da37f))
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