Drug intelligence / Profile preview

ACWY Vax

Development stage
Unknown
Lead developer
Sanofi Pasteur
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

ACWY Vax is a quadrivalent, inactivated polysaccharide vaccine developed by GSK for active immunization against invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, W-135, and Y. The vaccine is a biologic composed of purified capsular polysaccharides from these four bacterial serogroups, which act as the active immunogenic components. It works by stimulating the immune system to produce bactericidal antibodies against the capsular polysaccharides of these specific serogroups. Unlike conjugate vaccines, ACWY Vax consists of plain polysaccharides and does not contain live bacteria. It is administered via subcutaneous injection and is indicated for use in children from two years of age, adolescents, and adults, particularly those traveling to regions where meningococcal disease is endemic, such as for the Hajj or Umrah pilgrimage.

Brand names
ACWY Vax
Other names
Meningococcal polysaccharide vaccine groups A, C, W135 and YQuadrivalent meningococcal polysaccharide vaccine
02

Targets

Neisseria meningitidis group C capsular polysaccharideNmA CPS (Neisseria meningitidis group A capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)MenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)

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