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AD-223B is a small molecule drug developed by Addpharma for the treatment of essential hypertension. It is part of a combination therapy (AD-223A and AD-223B) evaluated in phase 3 clinical trials for efficacy and safety in patients with essential hypertension. The specific mechanism of action, molecular target, and detailed pharmacology have not been disclosed in public sources as of June 2025. The drug has not received regulatory approval yet but has completed phase 3 studies in Korea and the United States targeting cardiovascular diseases, specifically hypertension[2][3][5].
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