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ADC-042 is an antibody-drug conjugate (ADC) currently in preclinical development for the treatment of osteoporosis. It is being developed by iProgen Biotech in collaboration with the Korea Basic Science Institute (KBSI). The molecule utilizes iProgen's ADC platform, which involves a targeting antibody conjugated to a small-molecule payload. The program is designed to leverage the specificity of antibody-mediated delivery to modulate bone remodeling processes, aiming to provide a targeted therapeutic approach for bone loss. As of the current pipeline status, the specific biological target and the identity of the small-molecule payload have not been publicly disclosed.
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