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ADC 2 is a preclinical antibody-drug conjugate (ADC) being developed by Hexagon Bio for the treatment of solid tumors. The candidate utilizes a novel Protein Translation Inhibitor (PTI) payload, which is designed to disrupt the protein synthesis machinery within target cells to induce apoptosis. While the specific cell-surface antigen targeted by the antibody component remains undisclosed, ADC 2 represents part of Hexagon Bio's strategy to apply its discovery platform to identify and develop unique natural product-derived payloads for oncology applications.
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