Drug intelligence / Profile preview

adelmidrol + hyaluronic acid

Development stage
Unknown
Lead developer
Epitech
Modality
Small Molecules
Administration
Intranasal
01

Overview

Rinidrol is an intranasal spray developed by Epitech for the management of pediatric nasal and respiratory conditions, including inflammation and hyper-reactivity of the nasal mucosa. It is a combination product containing **adelmidrol**, a synthetic ALIAmide (Autacoid Local Injury Antagonism) analogue of palmitoylethanolamide, and **hyaluronic acid**. Adelmidrol acts by modulating mast cell degranulation and non-neuronal immune cell activity, thereby reducing local inflammatory responses. Hyaluronic acid provides a protective and hydrating barrier on the nasal mucosa, facilitating tissue repair and improving mucociliary clearance. The product is primarily marketed for pediatric use to treat conditions such as allergic rhinitis and respiratory tract inflammation.

Brand names
RinidrolRinidrol Spray Nasale
Other names
N,N'-bis(2-hydroxyethyl)nonanediamide + sodium hyaluronate
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)CD44 (CD44 antigen)

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