Drug intelligence / Profile preview

ADG10

Development stage
Discontinued
Lead developer
Invivyd
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

ADG10 is an investigational **neutralizing monoclonal antibody** against the **SARS-CoV-2 spike protein** that was developed by **Adagio Therapeutics** and later came under **Invivyd** following acquisition. It was designed as a biologic for the **treatment and prevention of COVID-19**, and was also described as a potential **cocktail partner** for ADG20 rather than a broadly commercialized standalone product. Preclinical reports indicated potent neutralizing activity against multiple SARS-CoV-2 variants of concern, including **P.1**, **B.1.351**, and **B.1.1.7**. Development appears to have been **discontinued**.

02

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)

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