Drug intelligence / Profile preview

Adiantum capillus-veneris extract

Development stage
Preclinical
Lead developer
Shiraz University of Medical Sciences
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Adiantum capillus-veneris extract, derived from the Southern maidenhair fern, is a botanical extract traditionally used in various folk medicine systems (such as Iranian traditional medicine, Ayurveda, and Unani) for respiratory, digestive, and inflammatory conditions. Phytochemical analysis reveals that the extract is rich in bioactive secondary metabolites, including flavonoids (such as rutin, quercetin, and kaempferol), phenolic acids, triterpenoids, saponins, and tannins. Preclinical studies have demonstrated that the extract possesses potent anti-inflammatory, antioxidant, antimicrobial, and antidiabetic properties. Notably, recent in vitro research has highlighted its potent antiviral activity against the influenza A virus (H1N1) strain, showing a synergistic effect when combined with the standard antiviral drug oseltamivir. It is currently investigated as a natural product or botanical extract rather than a targeted pharmaceutical development program.

Other names
Adiantum capillus-veneris hydroalcoholic extractAdiantum capillus-veneris L. extractBarshawshanBarsiawashanmaidenhair fern extractParsiaoshan
02

Targets

KATP channel (ATP-sensitive potassium channel)IL-6 (Interleukin 6)PGE2 (Prostaglandin E2)TNFA (Tumor necrosis factor alpha (soluble))Sucrase-Isomaltase

Beyond the preview

Go deeper on Adiantum capillus-veneris extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Adiantum capillus-veneris extract.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call