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Adiponexin

Development stage: Unknown
Lead developer: Realize Therapeutics
Modality: Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Peptides, Small Molecules, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Adiponexin is a probiotic-based body composition product developed by Realize Therapeutics. It is formulated as a combination of high-dose *Lactobacillus reuteri* LRDR™ (40 billion CFU), hydrolyzed marine protein, hyaluronan, and astaxanthin. Unlike traditional weight loss products, Adiponexin focuses on microbiome restoration to improve body shape by increasing muscle mass and reducing abdominal visceral fat. The product aims to restore keystone microbes lost in modern populations, leveraging the gut-muscle axis and metabolic modulation. It is typically administered as oral capsules and is intended to address body composition issues through microbiome replenishment rather than calorie restriction or stimulant-based mechanisms.

Brand names: Adiponexin

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