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Drug intelligence / Profile preview
AdoXLong Sema is a long-acting injectable formulation of the GLP-1 receptor agonist semaglutide, developed by Adocia using its proprietary AdoXLong platform. The technology involves a biocompatible polymer chemically linked to the peptide, which extends the drug's half-life to allow for once-monthly subcutaneous administration instead of the standard weekly dosing. This formulation is designed as a low-viscosity aqueous solution compatible with standard 29 Gauge needles. It is currently in preclinical development, with proof-of-concept achieved for the treatment of obesity and type 2 diabetes.
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