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adsorbed acellular diphtheria-tetanus-pertussis combined vaccine
- Development stage
- Unknown
- Lead developer
- Changchun BCHT Biotechnology
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The adsorbed acellular diphtheria-tetanus-pertussis combined vaccine is a trivalent combination vaccine (DTaP) developed by Changchun BCHT Biotechnology. It is designed to stimulate active immunity against pertussis (whooping cough), diphtheria, and tetanus. The vaccine is formulated with three-component acellular pertussis antigens, diphtheria toxoid, and tetanus toxoid, adsorbed onto an aluminum hydroxide adjuvant (specifically, a nano-aluminum adjuvant). It is administered intramuscularly. The vaccine has been evaluated in clinical trials in China, including a Phase I trial in healthy infants and children, and has progressed to Phase III development.
- Other names
- adsorbed acellular diphtheria-tetanus-pertussis (three-component) combined vaccineadsorbed acellular DTaP (three components) combined vaccinediphtheria, tetanus and acellular pertussis combined vaccine, adsorbed吸附无细胞百白破（三组分）联合疫苗百白破疫苗（三组分）
02
Targets
FHA (Filamentous hemagglutinin)PRN (Pertactin)Diphtheria toxin
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