Drug intelligence / Profile preview

adsorbed diphtheria + tetanus + acellular pertussis vaccine

Development stage
Unknown
Lead developer
Hualan Biological Bacterin
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The adsorbed diphtheria + tetanus + acellular pertussis vaccine, developed by Hualan Biological Vaccine Co., Ltd., is a trivalent combination vaccine designed for the active immunization of infants and children against diphtheria, tetanus, and pertussis (whooping cough). The vaccine contains purified diphtheria and tetanus toxoids, which are inactivated toxins that stimulate the production of neutralizing antibodies. The pertussis component is acellular, typically consisting of purified pertussis toxoid (PT) and filamentous hemagglutinin (FHA), which are safer alternatives to whole-cell pertussis vaccines. These antigens are adsorbed onto an aluminum-based adjuvant (such as aluminum hydroxide) to enhance the immune response. Upon administration, the vaccine induces a humoral immune response, creating a memory of the pathogens' toxins and surface proteins to prevent future infections and clinical disease caused by *Corynebacterium diphtheriae*, *Clostridium tetani*, and *Bordetella pertussis*.

Other names
DTaP vaccineDTPa vaccineacellular DTP vaccineadsorbed acellular diphtheria-tetanus-pertussis combined vaccine
02

Targets

Diphtheria toxinFHA (Filamentous hemagglutinin)

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