Drug intelligence / Profile preview

Advanced Phosphate Binder

Development stage
Unknown
Lead developer
LifeExtension
Modality
Small Molecules
Administration
Oral
01

Overview

Advanced Phosphate Binder is a dietary supplement formulated to assist in the management of serum phosphate levels by reducing the absorption of dietary phosphorus. The product's active ingredient is aluminum magnesium silicate, specifically a high-capacity, non-absorbable form known as NeoSorb. Its mechanism of action involves the sequestration of inorganic phosphate ions within the gastrointestinal tract. When taken with meals, the compound binds to phosphate to form an insoluble complex that is not absorbed by the intestinal mucosa and is subsequently excreted in the feces. This action effectively lowers the total amount of phosphate entering the systemic circulation, which is a critical consideration for individuals with compromised renal function or those at risk of hyperphosphatemia. The formulation is designed to be chemically stable across a wide pH range, ensuring consistent binding activity throughout the digestive process while minimizing the systemic absorption of aluminum or magnesium.

Brand names
Advanced Phosphate Binder
Other names
Aluminum Magnesium SilicateNeoSorb

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