Advantra Z

Advantra Z is a standardized, clinically studied extract of Citrus aurantium (bitter orange), primarily containing the protoalkaloid p-synephrine as its main active component. It is used as a dietary supplement ingredient for weight management, sports nutrition, and energy enhancement. The mechanism of action involves stimulation of beta-3 adrenergic receptors in adipose tissue and muscle, promoting thermogenesis (increased heat production) and lipolysis (breakdown of fat), which can increase resting metabolic rate and support fat loss. Unlike other stimulants such as ephedrine, Advantra Z has minimal impact on cardiovascular parameters like heart rate or blood pressure due to its selectivity for beta-3 over other adrenergic receptors. Multiple clinical studies have demonstrated its safety profile at recommended doses[1][2][4][5][6][7].

Brand names

Advantra Z

Other names

Citrus aurantium extractbitter orange extractp-synephrine (as primary active constituent)