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AERO-111
- Development stage
- Preclinical
- Lead developer
- AeroRx Therapeutics
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
AERO-111 is an IND-enabling, proprietary nebulized small-molecule triple-combination therapy being developed by AeroRx for chronic obstructive pulmonary disease. It combines a long-acting beta-2 adrenergic receptor agonist, a long-acting muscarinic M3 receptor antagonist, and an inhaled corticosteroid intended for patients who require escalation beyond dual bronchodilator therapy. The specific active ingredients have not been publicly disclosed.
- Other names
- Aero 111Aero111Aero-111
02
Targets
CHRM3 (M3)GR (Glucocorticoid receptor)ADRB2 (β2)
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