Drug intelligence / Profile preview

Aestox

Development stage
Unknown
Lead developer
Medytox
Modality
Recombinant Proteins and Enzymes
Administration
Intramuscular, Subcutaneous
01

Overview

Aestox is a highly purified (99.5%) formulation of Botulinum Toxin Type A developed by the South Korean company Medytox. It functions as a neuromuscular blocking agent by inhibiting the release of acetylcholine at the neuromuscular junction. Specifically, the toxin enters nerve terminals and cleaves the SNAP-25 protein, which is essential for the fusion of neurotransmitter vesicles with the presynaptic membrane. This action results in temporary muscle paralysis and chemical denervation. Aestox is primarily utilized for aesthetic procedures, including the reduction of dynamic facial wrinkles, masseter muscle reduction (jaw slimming), and body contouring (calf and arm reduction). It is also indicated for the treatment of focal hyperhidrosis, such as excessive armpit sweating. The product is certified by the Korea Food & Drug Administration (KFDA) and typically provides clinical effects lasting up to six months.

Brand names
Aestox
Other names
Botulinum Toxin Type A
02

Targets

SV2A (Synaptic vesicle glycoprotein 2A)SNAP25 (Synaptosome-associated protein 25)

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