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Drug intelligence / Profile preview
aframomum danielli extract
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Aframomum danielli extract is a botanical research compound derived from the seeds of *Aframomum danielli*, a plant in the Zingiberaceae family. It contains a variety of bioactive phytochemicals, including long-chain polyprenyl benzoquinone derivatives (such as phytylplastoquinone), alkaloids, and polyphenols. Preclinical studies have demonstrated its potential as an anti-inflammatory agent through the inhibition of arachidonate 5-lipoxygenase. Additionally, it has shown inhibitory activity against alpha-amylase and alpha-glucosidase, suggesting potential applications in glycemic management and diabetes. Other research has explored its antimicrobial properties against pathogens like *Salmonella typhi* and its effects on sexual health via phosphodiesterase 5 (PDE5) and arginase inhibition. It is currently not in formal clinical development and has no known commercial sponsor.
- Other names
- Aframomum danielli extractA. danielli extractAframomum danielli K. Schum extract
02
Targets
AMY (Pancreatic alpha-amylase)ALOX5 (Arachidonate 5-lipoxygenase)Sucrase-IsomaltaseARG1 (Arginase 1)GyrB (DNA gyrase subunit B)PDE5 (Phosphodiesterase 5A)
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