Drug intelligence / Profile preview

African Swine Fever vaccine (US Biologic)

Development stage
Preclinical
Lead developer
US Biologic
Modality
Vaccines & Immunotherapeutics
Administration
Oral
01

Overview

US Biologic is developing an oral vaccine for African Swine Fever (ASF) using its proprietary OrisBio platform. This platform utilizes *Bacillus subtilis* (*B. subtilis*) spores engineered to express specific African Swine Fever Virus (ASFV) antigens. When administered orally, these spores act as a delivery vehicle to the swine's gut-associated lymphoid tissue (GALT), where they elicit a protective immune response. The program is being developed in collaboration with the Department of Homeland Security (DHS) Plum Island Animal Disease Center and is currently in the preclinical stage of development.

Other names
ASFV oral vaccineOrisBio ASFV vaccineAfrican Swine Fever Virus (ASFV) oral vaccine
02

Targets

ASFV (African swine fever virus)

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