Drug intelligence / Profile preview

AGN-195263

Development stage
Phase 2
Lead developer
Allergan
Modality
Small Molecules
Administration
Topical, Ophthalmic
01

Overview

AGN-195263 is a small molecule drug developed as a topical ophthalmic treatment for eye disorders, primarily targeting meibomian gland dysfunction and evaporative dry eye. The drug was originally developed by Allergan and later by AbbVie following Allergan's acquisition. It reached phase III clinical trials for dry eyes and phase II for meibomianitis but development appears to have been discontinued. The precise mechanism of action remains undefined, but it was investigated as a new molecular entity for improving symptoms associated with tear film instability and eyelid gland dysfunction[1][2][3][4].

Other names
AGN 195263AGN195263AGN-195263
02

Targets

RARG (Retinoic acid receptor gamma)

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