Drug intelligence / Profile preview

AGN-231868

Development stage
Phase 2
Lead developer
AbbVie
Modality
Small Molecules
Administration
Ophthalmic, Topical
01

Overview

AGN-231868 is a small molecule chemokine receptor antagonist developed for the treatment of dry eye disease. It was originally developed by Allergan and is now under development by AbbVie. The drug acts by antagonizing chemokine receptors, which are involved in inflammatory pathways implicated in dry eye disease. AGN-231868 has been evaluated in Phase 2 clinical trials as a topical ophthalmic solution to assess its safety, tolerability, pharmacokinetics, and efficacy in patients with dry eye disease[2][3][4][5].

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